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VERFAHREN ZUR HERSTELLUNG EINER FESTEN PHARMAZEUTISCHEN ZUSAMMENSETZUNG, ENTHALTEND DEN WIRKSTOFF RASAGILIN
专利权人:
STADA ARZNEIMITTEL AG
发明人:
SCHÖNBORN, JESSICA,LORENZ, ANDREA
申请号:
EP13702727.2
公开号:
EP2804593A1
申请日:
2013.01.16
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention relates to a process for producing a solid pharmaceutical composition comprising the active ingredient rasagiline, comprising: dissolving a pharmaceutically acceptable rasagiline salt in an aqueous solvent to obtain a rasagiline salt solution admixing a solid carrier with the rasagiline salt solution. In order to provide a process by means of which compositions in which the rasagiline has elevated stability are obtainable and the composition can correspondingly be stored for longer, it is proposed that the pH of the rasagiline salt solution be adjusted to a value of less than 3.5 by means of a pharmaceutically acceptable acid.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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