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Heterocyclic janus kinase 3 inhibitors
专利权人:
ASTELLAS PHARMA INC.
发明人:
NAKAI, KAZUO,TANAKA, AKIRA,HAMAGUCHI, HISAO,MUKOYOSHI, KOICHIRO,SHIRAKAMI, SHOHEI,KUNIKAWA, SHIGEKI,SASAKI, HIROSHI,HIGASHI, YASUYUKI,INOUE, TAKAYUKI,HATANAKA, KEIKO,NAKAJIMA, YUTAKA,TAKAHASHI, FUMIE
申请号:
AU2006334044
公开号:
AU2006334044B2
申请日:
2006.12.25
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention provides a compound of formula (I) having an excellent JAK3 inhibition activity and being useful as an active ingredient of an agent for treating and/or preventing various immune diseases including autoimmune diseases inflammatory diseases, and allergic diseases. The compound according to the present invention has an inhibition activity against JAK3 and is thus useful as an active ingredient of an agent for treating or preventing diseases caused by undesirable cytokine signal transmission (e.g., rejection during organ/tissue transplantation, autoimmune diseases, multiple sclerosis, rheumatoid arthritis, psoriasis, asthma, atopic dermatitis, Alzheimer's disease, and atherosclerotic disease), or diseases caused by abnormal cytokine signal transmission (e.g., cancer and leukemia).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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