thieno [2,3-b] pyridine derivatives as viral replication inhibitors, their use in the manufacture of medicaments and as chemical tools in virology or biochemistry, method for preparing said compounds and pharmaceutical composition
ARNAUD MARCHAND,ARNOUT VOET,DAMIEN MARCHAND,DOROTHÉE BARDIOT,FRAUKE CHRIST,MARC DE MAEYER,PATRICK CHALTIN,ZEGER DEBYSER
申请号:
BRPI1010833
公开号:
BRPI1010833A2
申请日:
2010.05.17
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention relates to a series of compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutic amount of such compounds, optionally combined with one or more other drugs having anti-viral activity.