Systems and methods for non-invasive respiratory rate measurement are disclosed. In some embodiments, a system comprises a wearable member including an energy transmitter configured to project energy into tissue of a user. An energy receiver generates a multichannel signal based on a first received portion of the energy, the received portion of energy being received through the tissue of the user. A respiratory rate calculation system includes a pre-processing module for filter noise from the signal. A spectrum module determines a spectrum of the signal. A respiratory rate processing module determines a first respiratory rate from the spectrum of the signal. A noise reference and one or more second respiratory rates are obtained. A third respiratory rate is determined based on the first respiratory rate, the noise reference, and the one or more second respiratory rates. A communication module provides a message based on the third respiratory rate.