THE GENERAL HOSPITAL CORPORATION;TRUSTEES OF BOSTON UNIVERSITY
发明人:
EL-KHATIB, FIRAS,DAMIANO, EDWARD,RUSSELL, STEVEN J.
申请号：
CA2816314
公开号：
CA2816314C
申请日:
2011.10.31
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
A sensor-driven glucose control system, comprising a glucose sensor operativetocontinually measure glucose level of a subject and generate a correspondingglucose level signal；an insulin delivery device operative in response to an insulin dose controlsignal to infuse insulininto the subject； and a controller operative to generate the insulin dosecontrol signal in responseto the glucose level signal by: (1) modulating a basal infusion rate ofinsulin about a nominalbasal infusion rate in response to short-term variations of glucose leveloccurring on the order ofseconds to minutes； and (2) continually adjusting the nominal basal infusionrate based on amathematical relationship between the basal infusion rate as modulated and thenominal basalinfusion rate over a longer term than a short term associated with modulatingthe basal infusionrate.
