abstract the present invention relates to new kinase inhibitors, more specifically rock inhibitors, compositions, in particular pharmaceuticals, including such inhibitors, and uses of such inhibitors in the treatment and prophylaxis of disease. in particular, the present invention relates to new rock inhibitors, compositions, in particular pharmaceuticals, including such inhibitors, and uses of such inhibitors in the treatment and prophylaxis of disease. in addition, the invention relates to methods of treatment and use of said compounds in manufacture of a drug for application to a number of therapeutic indications including respiratory and gastro-intestinal diseases. abstract of patent summary for "soft rock inhibitors". The present invention relates to novel kinase inhibitors, more specifically rock inhibitors, particularly pharmaceutical compositions comprising such inhibitors, and the uses of such inhibitors in the treatment and prophylaxis of disease. in particular, the present invention relates to novel rock inhibitors, particularly pharmaceutical compositions comprising such inhibitors, and the uses of such inhibitors in the treatment and prophylaxis of disease. In addition, the invention relates to methods of treating and using said compounds in the manufacture of a medicament for application to a number of therapeutic indications, including respiratory and gastrointestinal disorders.abstract the present invention relates to new kinase inhibitors, more specifically rock inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. in particular, the present invention relates to new rock inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. in addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicame
