A Compound of formula (I), its tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and pharmaceutically acceptable compositions for use in the treatment of a liver disorder: ** Formula ** in which ---- represents an optional link； W represents O or S； Y represents NR4, S or O； wherein R4 represents hydrogen, substituted or unsubstituted groups selected from alkyl, alkenyl and aryl, a counterion or -CH2COR6； wherein R6 represents -OH, -NH2, -NHOH or OR18； wherein R18 is an alkyl group； Z represents -CR5 or S； R1 represents O, S or, together with R5, forms a 5 or 6-membered aromatic or heteroaromatic condensed ring system containing carbon atoms, or 1 or 2 heteroatoms selected from O, S or N； R2, R3 and R5 independently represent hydrogen, halogens, hydroxy, nitro, cyano, formyl, amino, alkyl, haloalkyl or alkoxy； R represents either U or V； wherein U represents hydrogen, halogen, hydroxy, nitro, cyano, formyl, amino, -COR10 or substituted or unsubstituted groups selected from linear or branched (C1-C6) alkyl group and (C1-C6) alkoxy group； R10 represents -OR11 or -NR12R13； wherein R11 represents hydrogen, substituted or unsubstituted groups selected from alkyl, alkenyl, aryl, aralkyl and heteroaryl, or a counterion； R12 and R13 independently represent hydrogen, or substituted or unsubstituted groups selected from alkyl, alkenyl, aryl and heteroaryl； or R12 and R13 together form a heteroaliphatic or heteroaromatic ring； V represents ** Formula ** R7 represents -OR14； wherein R14 represents hydrogen, substituted or unsubstituted groups selected from alkyl, alkenyl, aryl, aralkyl or heteroaryl, or a counterion； or -NR15R16； wherein R15 and R16 independently represent hydrogen or substituted or unsubstituted groups selected from alkyl, alkenyl, aryl and heteroaryl； R8 and R9 independently represent hydrogen, substituted or unsubstituted groups selected from alkyl, alkenyl, aryl and heteroaryl or -COR17； wherein R17 represent
