FELDMANN, PASCALE,FOWLER, JEFFREY DAVID,JHURRY, NEMA DEVI,MAILLET, ISABELLE,OMEDES PUJOL, MARTA
申请号：
CA3036620
公开号：
CA3036620A1
申请日:
2017.09.28
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention provides a method of substantially retaining or otherwise preserving the biological activity of a dsRNA, present in a cell, to post-transcriptionally silence the expression of a gene in a target organism, comprising the step of adding to the cell composition a compound having the function of a protein – or amine - cross linking agent and/or an acid. The invention also comprises compositions comprising the cells comprising dsRNA, and protein cross linking agents and/or acids, as well as the use of said cross linking agents and/or acids in the method.
