PROBLEM TO BE SOLVED: To provide a compound obtained by bioconversion of karahanaenone, and a cyclooxidase-2 inhibitor containing the compound as an active ingredient.SOLUTION: The present invention relates to a compound represented by the specified general formula (II) (in the formula, Rrepresents H or OR, where Rrepresents H or a protecting group of a hydroxy group; and Rrepresents ORwhen Ris H, and represents H when Ris OR), and to a cyclooxidase-2 inhibitor containing the compound as an active ingredient.