FIELD: chemistry.SUBSTANCE: invention relates to organic chemistry, in particular, to derivatives of imidazo[5,1-a]isoindole of structure given below, or to a stereoisomer or pharmaceutically acceptable salt thereof, where bond α is a single or double bond； n = 0 or 1； R1: halogen or -OR； R2: -C1-4alkyl-RA or -C2-4alkenyl-R3, if bond α is a single bond； and R2: =C(H)RA, if bond α is a double bond； in which RA: -CN, -C(O)R3, -C(O)OR3, -C(O)N(R3)(RC), -C(ORB)(R3)(RC), -C(NHRB)(R3)(RC), or -C(=N-ORC)R3, where RB: hydrogen, -C(O)R3, -C(O)N(H)R3, -C(O)(CH2)2COOR, -C(O)(CH2)1-4(NR)COOR, -C(O)CH(NH2)(RD), or -P(O)(OR3)2； where RD: methyl or -CH(CH3)2； R3: hydrogen, C1-6alkyl, phenyl, imidazolyl, furanyl, thiazolyl, pyridinyl, C5-6cycloalkyl, C3-8cycloalkenyl, piperidinyl, pyrrolidinyl, tetrahydropyranyl, azetidinyl or C6cycloalkylC1alkyl-, where each alkyl, cycloalkyl, piperidinyl, pyrrolidinyl, tetrahydropyranyl and azetidinyl is optionally and independently substituted with one group =R32 and optionally and independently substituted with one or two groups R31； each phenyl, imidazolyl, furanyl, thiazolyl and pyridinyl is optionally substituted with one or two groups R31； where R31: halogen, nitro, C1-6alkyl, -C1-6alkyl-R33, C1-6haloalkyl, -OR, -N(R)2, -C(O)OR, -C(O)N(R)2, -C(O)R, -S(O)2R, -OC(O)R, -N(R)C(O)R or -N(R)C(O)OR, where R33: -OR； R32: =O, =C(R34)2, =(spiro-C3-8cycloalkyl), or =(spirodioxalanyl), where R34: hydrogen, halogen, C1-6alkyl or -C1alkyl-OR； RC: hydrogen or C1-6alkyl； and R: hydrogen or R10, where R10: C1-6alkyl, phenyl, thiophenyl, C5-6cycloalkyl, pyrrolidinyl, tetrahydropyranyl, phenylC1-6alkyl, heteroarylC1-2alkyl- (where heteroaryl group is a pyridine, pyrimidine or imidazole) or tetrahydropyranC1alkyl, where each of alkyl, phenyl, cycloalkyl and phenylC1-2alkyl optionally substituted with one or two groups, which independently represent a halogen, C1-6alkyl, C1haloalkyl, -OR11, -N(R11)2 or -N(R11)S(O)2R11, where R11: hydrogen or C1-6alkyl. Inventio
