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Polymeric delivery formulations of leuprolide with improved efficacy
专利权人:
Richard L. Dunn;John Steven Garrett;Harish Ravivarapu;Bhagya L. Chandrashekar
发明人:
Richard L. Dunn,John Steven Garrett,Harish Ravivarapu,Bhagya L. Chandrashekar
申请号:
US12784304
公开号:
US08486455B2
申请日:
2010.05.20
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is directed to a flowable composition that is suitable for use as a controlled release implant. The flowable composition includes a biodegradable thermoplastic polyester that is at least substantially insoluble in aqueous medium or body fluid. The flowable composition also includes a biocompatible polar aprotic solvent. The biocompatible polar aprotic solvent is miscible to dispersible in aqueous medium or body fluid. The flowable composition also includes leuprolide acetate.
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