Provided herein is inhibit Elixirs and JAK that Elixirs Group is inhibited to close Treatment method comprising mTOR. Suo Shu Group closes Treatment method and controls Treatment Duo Seed cancer, including MPN with what. Suo Shu Group closes Treatment method and also controls Treatment Duo Seed JAK- Xiang Off disease with what.本文提供包含mTOR抑制劑和JAK抑制劑的組合療法。所述組合療法用於治療多種癌症,包括MPN。所述組合療法也用於治療多種JAK-相關疾病。