WU, Edwin SC,CHIU, Peter JS,HSU, Mei-chi,SHIH, Ying-Chu
申请号:
EP16769679
公开号:
EP3273958A4
申请日:
2016.03.24
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention relates to new medical uses of morphinans such as naltrexone, nalmefene and their related derivatives. The present invention relates to Toll-like receptor 4 (TLR4) antagonist compounds, and pharmaceutical formulations thereof, and use thereof for prevention and treatment of autoimmune liver diseases including but not limited to autoimmune hepatitis.