A method is provided and may include accessing a terminal branch of an ophthalmic artery through a skin of a head of a subject via a first device, positioning at least one of the first device or a second device within the ophthalmic artery of the subject, and performing an atherectomy of the ophthalmic artery or a junction between the ophthalmic artery and an internal carotid artery of the subject, using the at least one of the first device or the second device, so as to treat a blockage, a stenosis, a lesion, plaque, or other physiology in the ophthalmic artery or the junction between the ophthalmic artery and the internal carotid artery of the subject.