Haris J. Sih;Prashant Sinha;Jihong Qu;Mark Schwartz
发明人:
Jihong Qu,Haris J. Sih,Mark Schwartz,Prashant Sinha
申请号:
US11895025
公开号:
US08311620B2
申请日:
2007.08.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides a cardiac rhythm management system which includes a tachyarrhythmia detection and classification circuit programmed to detect and classify a tachyarrhythmia, a biologic therapy delivery device configured to deliver or regulate an expression cassette suitable for terminating or preventing atrial fibrillation (AF), and a control circuit coupled to the tachyarrhythmia detection and classification circuit and the biologic therapy delivery device. Also provided is an implantable medical device for use in a body having a cardiovascular system, which includes an implantable device body including at least a cardiovascular portion configured to be in the cardiovascular system, and an expression cassette incorporated into the cardiovascular portion of the implantable device body, the expression cassette selected to express a gene product that terminates or prevents AF. Further provided are methods which employ particular expression cassettes to prevent, inhibit or treat AF.