The present invention relates to IL-17A binding molecule and uses thereof, particularly relates to a humanized antibody which can recognize and combined to IL-17A specifically. The present IL-17A binding molecule can be uses in the treatment of inflammatory and autoimmune diseases induced by high expression of interleukin-17A, including psoriasis, psoriatic arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory arthritis, and etc.本發明涉及IL-17A結合物及其用途。尤其涉及一種特異性識別IL-17A並能與IL-17A結合的人源化抗體。可用於治療因介白素-17A高表達引起的炎症和自身免疫疾病，包括銀屑癬，銀屑病關節炎，僵直性脊椎炎，多發性硬化症，炎性關節炎等。
