PROBLEM TO BE SOLVED: To solve the following problem that conventionally, a surface of a medical placement device, a part of which is inside the body, is made to contain antibacterial drug or antithrombotic drug to prevent the formation of biofilm or blood clot due to bacterial adhesion, but an expiration date arrives soon and its extension is required.SOLUTION: By pasting a vibration element on a part outside a body of the medical placement device to vibrate the medical placement device in its long axis direction and by controlling its vibration strength or the number of times of its vibration, an elution time for active medicinal agent is extended.COPYRIGHT: (C)2013,JPO&INPIT【課題】従来体内にその一部があるメデイカル留置デイバイスの表面に抗菌薬や抗血栓薬を含有さし、細菌付着によるバイオフイルムや血栓形成を防止していたが、有効期限が短かくその延長が求められていた。【解決手段】メデイカル留置デイバイスの体外部分に振動素子を貼り付けて、メデイカル留置デイバイスをその長軸方向に振動さし、かつその振動強度又は振動数を制御することで、有効薬剤溶出時間を延長する。【選択図】図1
