Heidi Okamura,Sandra Abbott,Alisa C. Bell,Kelly Kreuter,Ronan O'Hagan,Samantha Perino,Hamid Tissire,William M. Winston, Jr.,Jeno Gyuris,Ronan OHagan
申请号:
US14653684
公开号:
US09879083B2
申请日:
2013.12.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Monoclonal antibodies that bind and inhibit activation of human Notch3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of Notch3.