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HIV DNA vaccine methods of use
专利权人:
Zhenqian Liu
发明人:
Opendra Narayan,Zhenqian Liu
申请号:
US13185158
公开号:
US08785411B2
申请日:
2011.07.18
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for use as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3′ LTR.
来源网站:
中国工程科技知识中心
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