This invention relates to an absorbable sterile injectable aqueous formulation that is ready to use, used for therapeutic purposes as a cohesive particle-based viscoelastic gel containing i) cross-linked hyaluronic acid, or one of its salts, at a concentration between 1% and 4% (mass/volume), with the cross-linking that is performed making it possible to obtain a gel having a base of cross-linked hyaluronic acid having a so-called cohesive structure, and ii) hydroxyapatite. at a concentration between 10% and 70% (mass/volume), said hydroxyapatite being in the form of particles having an average size less than or equal to 650 μm； with the said sterile injectable aqueous formulation having viscoelastic properties such that Tanδ at a frequency of 1 Hz is less than or equal to 0.60.本發明係關於一種用於治療目的之呈基於內聚性粒子之黏彈性凝膠形式的即用型可吸收無菌可注射水性調配物，其含有i)濃度為1%至4%(質量/體積)之交聯玻尿酸或其鹽中之一者，其中進行該交聯從而使得有可能獲得具有所謂之內聚性結構之具有交聯玻尿酸基質的凝膠，及ii)濃度為10%至70%(質量/體積)之羥磷灰石，該羥磷灰石呈平均尺寸小於或等於650μm的粒子形式；該無菌可注射水性調配物具有黏彈特性從而使得在1Hz之頻率下的Tanδ小於或等於0.60。
