THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
发明人:
David A. Zaharoff,Suresh Kumar Thallapuranam,Bhanu prasanth Koppolu,Srinivas Jayanthi,Sean G. Smith
申请号:
US15315097
公开号:
US20170106092A1
申请日:
2015.06.01
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Compositions including chitosan covalently linked to a cytokine or growth factor are provided herein. The compositions can be used to produce pharmaceutical compositions and can be used in methods of treating a variety of diseases or disorders. The compositions are especially suitable for localized delivery and may allow for intratamoral delivery and treatment of cancers or stimulation of an immune response to a co-administered antigen.