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Kappa opioid receptor antagonists and products and methods related thereto
专利权人:
Blackthorn Therapeutics, Inc.;The Scripps Research Institute
发明人:
Roberts, Edward,Guerrero, Miguel A.,Urbano, Mariangela,Rosen, Hugh,Jones, Robert M.,Laxamana, Candace Mae,Zhao, Xianrui,Turtle, Eric Douglas
申请号:
AU2018234931
公开号:
AU2018234931A1
申请日:
2018.03.16
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Compounds are provided that antagonize the kappa-opioid receptor (KOR) and products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope or salt thereof: (I) wherein X, Y, R
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