MOSLIN, Ryan M.,WEINSTEIN, David S.,WROBLESKI, Stephen T.,ZHANG, Yanlei,TOKARSKI, John S.,MERTZMAN, Michael E.,LIU, Chunjian
申请号：
HUE14702707
公开号：
HUE046052T2
申请日:
2014.01.16
申请国别(地区):
HU
年份:
2020
代理人:
摘要：
Compounds having the following formula I:or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R<；sup>；1<；/sup>；, R<；sup>；2<；/sup>；, R<；sup>；3<；/sup>；, R<；sup>；4<；/sup>；, and R<；sup>；5<；/sup>；are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα by acting on Tyk-2 to cause signal transduction inhibition.
