The present invention relates to novel compounds of formula (I), its pharmaceutically acceptable salts, and isomers, stereoisomers, atropisomers, conformers, tautomers, atropisomers, polymorphs, hydrates, solvates, N-oxide or S-oxide thereof. The present invention also relates to pharmaceutically acceptable compositions and process for preparing said compounds. The invention further relates to the use of the above-mentioned compounds for the preparation of medicament for use as pharmaceuticals.本發明與分子式(I)的創新化合物、其藥學上可接受鹽類以及其異構物、立體異構物、阻轉異構物、構形異構物、互變異構物、阻轉異構物、同素異形體、水合物、溶劑化物、N-氧化物或S-氧化物有關。本發明也與用於製備該化合物的藥學上可接受的組合物以及過程有關。本發明進一步與用於製備作為藥物的藥劑的上述化合物的用途有關。