MINNESOTA MINING & MANUFACTURING COMPANY; SAINT PAUL
发明人:
BEAURLINE, JOSEPH M.,RODDY, PATRICK J.,TOMAI, MARK A.
申请号：
HU0000568
公开号：
HU229599B1
申请日:
1997.12.01
申请国别(地区):
HU
年份:
2014
代理人:
摘要：
Pharmaceutical gel formulations for topical drug delivery include drug, colloidal silicon dioxide, triacetin and, preferably, propylene glycol. The gel formulations are well suited for topical delivery of the drug 4-amino-2-ethoxymethyl-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol, which when applied topically induces cytokines, such as interferon and tumor necrosis factor, locally in the skin or mucous membranes of a mammal. The gel formulations are also well-suited for topical delivery of drugs for treatment of diseases involving skin and/or mucosal lesions because the gel formulations do not need to include irritating components.
