GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
WAN, ZEHONG,ZHANG, XIAOMIN
申请号:
CA2899124
公开号:
CA2899124A1
申请日:
2014.01.23
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention relates to novel 3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.