Gabriel M. Gutierrez,Vinayaka Kotraiah,James Pannucci,Ramses Ayala
申请号：
US15908861
公开号：
US20180185474A1
申请日:
2018.03.01
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This disclosure provides peptides which have a strong affinity for the checkpoint receptor “programmed death 1” (PD-1). These peptides block the interaction of PD-1 with its ligand PD-L1 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer, treating infectious diseases, enhancing a response to vaccination, and treating sepsis.
