This invention provides an extract of inflamed rabbit skin induced by inoculation of vaccinia virus, which has more stable quality, and preparations containing the extract as effective ingredient. Through using the content of sulfated tyrosine in the extract of inflamed rabbit skin induced by inoculation of vaccinia virus and the preparation containg the extract as indicator, the better quality stablity of each manufacturing lot of the eextract and the preparation can be ensured. By the above method, it can be guaranteed that the extract of inflamed rabbit skin induced by inoculation of vaccinia virus and the preparation containg the extract with more stable quality thus obtained, become more effective and safer, accordingly very useful.本發明之目的為提供品質較為安定的牛痘病毒接種兔子炎症皮膚萃取物及含有該萃取物作為有效成分之製劑等。藉由以在牛痘病毒接種兔子炎症皮膚萃取物及含有該萃取物之製劑中所含有之硫酸化酪胺酸之量作為指標，可確保該萃取物及製劑之每一製造批號的品質成為較安定者。藉由此種方法使品質變得較安定的牛痘病毒接種兔子炎症皮膚萃取物及含有該萃取物之製劑，其之有效性及安全性被更嚴格擔保，而成為在有用性上非常高者。
