Method for producing a bone prosthesis, comprising forming a surgical guide (1) equipped with at least one artificial prosthesis (150 and with at least a first hole passing through each artificial prosthesis in a predetermined orientation, placing the surgical guide on a model (2), drilling a second hole (16) through the model with the aid of a drill (8) passed through each first hole, the passage of the drill through the corresponding first hole taking place without contact therewith, and guiding the drill in said predetermined orientation with the aid of drill introduction means (10, 11) situated outside said first hole.
