Alexey G. Ryazanov,Alexander V. Chikunov,Yuriy Shymkiv
申请号：
US15784869
公开号：
US20180256617A1
申请日:
2017.10.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present disclosure relates to methods of extending the lifespan of a subject or treating, suppressing, inhibiting or delaying the onset of an age-related condition or disorder, such as cancer, in a subject. The methods comprise administering to the subject an effective amount of (i) a compound that sustains pharmacological activation of xenobiotic metabolism, (ii) a cardiac glycoside, (iii) a chelator, (iv) inulin, (v) D-valine, or any combination thereof. In a further aspect, the present disclosure relates to a method of identifying clinical candidates by performing a high throughput screening in mammals of test compounds which have great structural and/or functional diversity.
