VASCULAR ENDOTHELIAL GROWTH FACTOR ANTAGONISTS AND METHODS FOR THEIR USE

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专利权人:

发明人:

申请号：

EP13720737.9

公开号：

EP2841087A1

申请日:

2013.04.26

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The present invention provides variant VEGF polypeptides which have been altered in their C-terminal heparin binding region to lower their heparin binding affinity. These variants have been found to act as receptor antagonists for VEGF receptors and antagonize angiogenesis. These variants are useful to treat diseases characterized by pathological angiogenesis.

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中国工程科技知识中心

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