Treatment of cancer using a CLL-1 chimeric antigen receptor

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专利权人:

The Trustees of the University of Pennsylvania;Novartis AG

发明人:

Brogdon, Jennifer,Ebersbach, Hilmar,Gill, Saar,Glass, David,Jascur, Julia,Kenderian, Saad,Mannick, Joan,Milone, Michael C.,Murphy, Leon,Richardson, Celeste,Singh, Reshma,Wei, Lai,Wu, Qilong,Yang, Qium

申请号：

AU2020201939

公开号：

AU2020201939A1

申请日:

2020.03.18

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

#$%^&*AU2020201939A120200409.pdf#####Abstract The invention provides compositions and methods for treating diseases associated with expression of CLL-1. The invention also relates to chimeric antigen receptor (CAR) specific to CLL-1, vectors encoding the same, and recombinant cells comprising the CLL-1 CAR. The invention also includes methods of administering a genetically modified cell expressing a CAR that comprises a CLL-1 binding domain.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/