The present invention provides compositions and methods of their administration for the protection of cells and tissues from damage caused by FROS in the body of an individual. Compositions comprising halogenated phenol compounds are provided that scavenge or consume FROS in the body. These FROS scavenging compounds may not only protect cells and tissues from damage, but also treat disease and/or alleviate the symptoms of disease associated with high FROS levels. Sunscreen compositions comprising FROS-scavenging compounds of the present invention are further provided to reduce the damaging effects of sunlight on the skin of an individual.
