Compounds derived from pyrimidine triazin Amine or Amine, inhibitors of DNA PK； Pharmaceutical Composition and its use for the treatment of cancer.

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专利权人:

INC.;VERTEX PHARMACEUTICALS

发明人:

GAO, HUAI,CHARIFSON PAUL S.,COTTRELL KEVIN MICHAEL,DUFFY JOHN P.,GIROUX SIMON,GREEN JEREMY,JACKSON KATRINA LEE,MAXWELL JOHN PATRICK,MORRIS MARK A.,PIERCE ALBERT CHARLES,WAAL NATHAM D.,LAUFFER DAVID J.

申请号：

CL2014002873

公开号：

CL2014002873A1

申请日:

2014.10.24

申请国别(地区):

CL

年份:

2015

代理人:

摘要：

The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.COMPUESTOS DERIVADOS DE 8-(1-{[6-(PIRIDIN-3-IL O PIRIMIDIN-5-IL)PIRIMIDIN-4-IL]AMINO}PROPAN-2-IL)QUINOLINA, INHIBIDORES DE ADN-PK； COMPOSICIÓN FARMACÉUTICA； Y SU USO PARA EL TRATAMIENTO DEL CÁNCER.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/