MAATTA, ANN-MARIE,SAMARANAYAKE, HARITHA,PIKKARAINEN, JERE,YLA-HERTTUALA, SEPPO
申请号：
CA2824689
公开号：
CA2824689A1
申请日:
2012.01.18
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
An agent comprises a vector having a functional gene, a prodrug which can be converted into a cytotoxic agent by an expression product of the gene, and another cytotoxic agent,as a combined preparation for simultaneous, sequential or separate use in the therapy of cancer or of a disease characterised by an impaired mismatch repair (MMR) pathway, wherein the dosage regimen comprises beginning the another cytotoxic agent therapy no later than 7 days after the prodrug therapy has finished.
