PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS ASSOCIATED WITH NEURODEGENERATIVE DISEASE OR IMPULSIVE SYMPTOMS ASSOCIATED WITH MENTAL DISEASE CONTAINING BREXPIPRAZOLE OR SALT THEREOF
SATO SHINJI,佐藤 慎二,MAEDA KENJI,前田 健二,ISHIKAWA MASARU,石川 大,NAKAMURA MAI,中村 舞
申请号：
JP2018065319
公开号：
JP2018138555A
申请日:
2018.03.29
申请国别(地区):
JP
年份:
2018
代理人:
摘要：
PROBLEM TO BE SOLVED: To provide a prophylactic and/or therapeutic agent for behavioral and psychological symptoms associated with dementia.SOLUTION: The present invention provides a prophylactic and/or therapeutic agent for behavioral and psychological symptoms associated with dementia, containing 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one, of the following formula, or a salt thereof as an active ingredient. The agent is useful against psychological symptoms associated with dementia, including depression, anxiety, hallucination, delusion, sleep disorder and the like, and impulsive symptoms including violence, violent language, wandering, rejection, unclean behavior and the like.SELECTED DRAWING: Figure 2【課題】認知症に伴う周辺症状に対する予防及び／又は治療剤の提供。【解決手段】下記式で表される７－［４－（４－ベンゾ［ｂ］チオフェン－４－イル－ピペラジン－１－イル）ブトキシ］－１Ｈ－キノリン－２－オン又はその塩を有効成分とする、認知症に伴う周辺症状の予防及び／又は治療剤。前記剤は、認知症に伴う周辺症状である、抑うつ、不安、幻覚、妄想、睡眠障害等の精神症状、並びに暴力、暴言、徘徊、拒絶、不潔行為等の衝動性症状の予防及び／又は治療に有用である。【選択図】図２
