Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)
发明人:
申请号：
EP18382765.8
公开号：
EP3646889A1
申请日:
2018.10.30
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
In the present invention, we have found when iron oxide nanoparticles are doped with Cu (copper), a significant increase in the value of r1 is achieved (see figure 7), a value which measures the capacity of a contrast agent to provide a bright signal. "Normal" values of contrast agents for clinical use have values in the 4-6 range. In contrast, Cu-doped iron oxide nanoparticles (CuIONP), provide values of 16 mM-1s-1.
