A system for managing power consumption of a handheld diabetes management device and limiting effects of temperature on operations performed by the handheld diabetes management device comprises a blood glucose measuring module, a temperature sensing module, and a power management module. The blood glucose measuring module selectively measures blood glucose in a blood sample and generates a status signal indicating a status of operation of the blood glucose measuring module. The temperature sensing module senses an internal temperature of the handheld diabetes management device and estimates an ambient temperature external to the handheld diabetes management device. The power management module deactivates one or more components of the handheld diabetes management device based on the status of operation of the blood glucose measuring module when the internal temperature of the handheld diabetes management device exceeds a threshold temperature. The power management module deactivates the blood glucose measuring module when the ambient temperature is greater than a first predetermined threshold or less than a second predetermined threshold.本発明は、携帯型医療機器(104)の電力消費を管理するシステムに関し、システムは、携帯型医療機器(104)の内部温度を感知する温度センサ(605)、携帯型医療機器(104)の外部の周囲温度を予測するために熱的モデルを使用する熱的モデリングモジュール(602)、および、周囲温度が閾値温度を超えるときに携帯型医療機器(104)の1つまたは2つ以上の構成要素を非活性化するように適合される電力管理モジュール(600)を含む。