ROGER UNGER,JEF DE BRABANDER,MICHAEL ROTH,MATTHEW EVANS
申请号：
US14448247
公开号：
US20150037361A1
申请日:
2014.07.31
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The described invention provides methods and compositions for treating diabetes and hyperglycemia in a mammal comprising administering to the mammal a therapeutic amount of a glucagon depleting compound. Also provided are methods and compositions for eliciting a bihormonal response in a mammal comprising administering to the mammal a therapeutic amount of a glucagon depleting compound. The glucagon depleting compound is effective to normalize glucagon, insulin, glucose, glycated hemoglobin (HgAlC) and C peptide in a mammal suffering from diabetes.
