Disclosed is a quinazolinedione derivatives of formula (I) with A being a sulphur or oxygen atom or a sulphoxide or a sulphone group, methods for obtaining same and therapeutic uses thereof, such as cancer, diabetes, muscle diseases, bone diseases, cardiovascular diseases, central nervous system diseases, peripheral nervous system diseases. Examples of compounds of formula (I) are 3-(3,4-dimethoxybenzyl)-6-hydroxy-1-(tetrahydro-2H-pyran-4-yl)quinazoline-2,4(1H,3H)-dione ([3-(3,4-dimethoxybenzyl)-2,4-dioxo-1-(tetrahydro-2H-pyran-4-yl)-1,2,3,4-tetrahydroquinazolin-6-yl]oxy} acetonitrile and 3-(3,4-dimethoxybenzyl)-6-pyridin-4-yl-1-(tetrahydro-2H-pyran-4-yl)quinazoline-2,4(1H,3H)-dione hydrochloride.
