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Synthetic myostatin peptide antagonists
专利权人:
MYOSTIN THERAPEUTICS PTY LTD
发明人:
BOWER ROBERT SYNDECOMBE,DE MOURA MONICA SENNA SALERNO,NICHOLAS GINA DIANE,THOMAS MARK FRANCIS,BERRY CAROLE JUDITH
申请号:
NZ59960410
公开号:
NZ599604A
申请日:
2010.09.29
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is a synthetic peptide having myostatin antagonist activity, having an amino acid sequence corresponding to at least five contiguous amino acids of a mature myostatin peptide of SEQ ID NO:1, wherein the synthetic peptide comprises at least two cysteine residues at positions 281 and 282 which are forced to bond and form a disulfide bond wherein the sequence identity is as disclosed in the specification. Also disclosed is the use of the said peptide in regulating muscle growth.
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