LEE, JAE HWAKR,이재화,CHOI, SOO JEONGKR,최수정,JEONG, NAM OCKKR,정남옥
申请号:
KR1020150167330
公开号:
KR1020170062017A
申请日:
2015.11.27
申请国别(地区):
KR
年份:
2017
代理人:
摘要:
The present invention relates to an anticancer composition comprising an extract of Cladosiphon novae-caledoniae Kylin as an active ingredient. Specifically, the present invention relates to an anticancer composition, a pharmaceutical composition for treating or preventing cancers, or a food composition for alleviating or preventing cancers, all of which comprise an extract of Cladosiphon novae-caledoniae Kylin as an active ingredient, and are prepared by a method comprising the following steps: a crude extract preparation step of adding an aqueous solvent to Cladosiphon novae-caledoniae Kylin, and performing an extraction under high pressure at 121°C for one hour to prepare a crude extract a Cladosiphon novae-caledoniae Kylin dietary fiber separation step of performing centrifugation of the crude extract at 3,000 rpm for 20 minutes to obtain an overlying liquid and a Cladosiphon novae-caledoniae Kylin water-soluble dietary fiber extraction step of adding ethanol twice the volume of the overlying liquid to the overlying liquid, refrigerating the same at 4°C for 24 hours, and then performing centrifugation of the same at 3,000 rpm for 20 minutes to obtain a sedimented material. The active ingredient of the present invention, water-soluble dietary fiber extract of Cladosiphon novae-caledoniae Kylin has superior anticancer effects and antioxidant effects compared to dietary fibers prepared using other solvents. Additionally, by using the water extract of a natural material that is an edible plant that has been used for a long time as the active ingredient, the present invention has few side effects, and thus has significant industrial effects.COPYRIGHT KIPO 2017본 발명은 큰실말 추출물을 유효성분으로 포함하는 항암 조성물에 관한 것이다. 구체적으로, 본 발명은 큰실말에 수용매를 첨가하고, 121℃에서 1시간 동안 고압 추출하여 조추출물을 제조하는 조추출물 제조 단계 상기 조추출물을 3,000 rpm의 조건으로 20분간 원심분리한 후, 상등액을 수득하는 큰실말 수용성 식이섬유 분리 단계 및 상기 상등액에 부피 기준으로 상기 상등액의 2배에 해당하는 에탄올을 첨가하고, 4℃에서 24시간 동안 냉장보관 후, 3,000 rpm의 조건으로 20분간 원심분리한 다음, 침전물을 수득하는 큰실말 수용성 식이섬유 추