An ECG electrode lead system suitable for use during imaging procedures such as, without limitation, CT scans or MRI and methods of use. The a radiolucent ECG lead set cable includes at least one radiolucent conductor, at least one radiolucent electrode connector operatively coupled to a distal end of the ECG lead set cable, an ECG intermediate lead set connector disposed at a proximal end of the ECG lead set cable, and an ECG lead extension assembly.