COMPOSÉS ET PROCÉDÉS POUR MODULER L'INTERACTION ENTRE DES PROTÉINES ET DES ACIDES NUCLÉIQUES CIBLES

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专利权人:

COLD SPRING HARBOR LABORATORY; INC.;ISIS PHARMACEUTICALS;ISIS PHARMACEUTICALS, INC.

发明人:

RIGO, FRANK,BENNETT, C., FRANK,KRAINER, ADRIAN, R.,HUA, YIMIN

申请号：

EP11796395

公开号：

EP2582397A4

申请日:

2011.06.15

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

Provided herein are antisense compounds and methods for recruiting one or more non-cleaving protein to a target nucleic acid in a cell. In certain instances such recruitment of a non-cleaving protein alters the function or activity of the target nucleic acid. In certain such instances, the target nucleic acid a pre-mRNA and the recruitment of the non-cleaving protein results in a change in splicing of the pre-mRNA.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/