Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
Hentemann Martin,Wood Jill,Scott William,Michels Martin,Campbell Ann-Marie,Bullion Ann-Marie,Rowley Bruce R.,Redman Aniko
申请号:
US201715398916
公开号:
USRE46856(E1)
申请日:
2017.01.05
申请国别(地区):
美国
年份:
2018
代理人:
White & Case LLP
摘要:
This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyperproliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.