COMPOUNDS AND METHODS FOR DEVELOPMENT OF RET MODULATORS

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专利权人:

PLEXXIKON INC.

发明人:

IBRAHIM PRABHA,IBRAHIM Prabha,WEST BRIAN,WEST Brian,KUMAR ABHINAV,KUMAR Abhinav,KRUPKA HEIKE,KRUPKA Heike,ZUCKERMAN REBECCA,ZUCKERMAN Rebecca,ZHU YONG,ZHU Yong,ZHANG JIAZHONG,ZHANG Jiazhong,ZHANG CHAO

申请号：

SI200432217

公开号：

SI1696920T1

申请日:

2004.12.17

申请国别(地区):

SI

年份:

2015

代理人:

摘要：

Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crystals and structural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/