Xiaomin Zhang;Hubo Wang;Wei Song;Zhedong Yuan;Hongjiang Xu;Xueyan Zhu;Hui Fu
发明人:
Zhedong Yuan,Xiaomin Zhang,Hubo Wang,Xueyan Zhu,Hongjiang Xu,Hui Fu,Wei Song
申请号:
US12994442
公开号:
US08829039B2
申请日:
2009.05.25
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed are dihydroindolone compounds which can modulate the activity of protein tyrosine kinases, a method for preparing the same, and pharmaceutical compositions comprising the same. Also disclosed are use of such compounds and pharmaceutical compositions thereof in the treatment and/or prophylaxis of protein tyrosine kinase associated diseases in an organism, particularly in the treatment and/or prophylaxis of tumors and fibroblast proliferation associated diseases.