MULTIVALENT IMMUNOGENIC CONJUGATES AND PREPARATION THEREOF

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专利权人:

发明人:

KAPRE SUBHASH VINAYAK,MALLYA Asha Dinesh,BORE Prashant Vasudeo,BHADURI Tamal Dilipkumar,SHENDE Niraj Vijay

申请号：

IN133/MUM/2012

公开号：

IN2012MU00133A

申请日:

2012.01.13

申请国别(地区):

IN

年份:

2013

代理人:

摘要：

The current invention provides improved methods for preparing immunogenic conjugates wherein multiple bacterial capsular polysaccharides are linked to a single type of carrier protein,particularly polysaccharide-protein bivalent conjugates by utilizing cyanylating agent other than CDAP,resulting in optimal conjugation efficiency.Also immunogenicity of said bivalent conjugates is equivalent to that of monovalent conjugates.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/