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Combination of a phosphoinositide 3-kinase inhibitor and a modulator of the Janus Kinase 2-Signal Transducer and Activator of Transcription 5 pathway
专利权人:
Novartis AG
发明人:
Bentires-ALJ, Mohamed,Britschgi, Adrian
申请号:
AU2012338869
公开号:
AU2012338869A1
申请日:
2012.11.14
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The invention relates to a pharmaceutical combination which comprises (a) a phosphoinositide 3-kinase inhibitor compound and (b) a compound which modulates the JAK2-STAT5 pathway for the treatment of a proliferative disease, especially a solid tumor disease; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of a proliferative disease; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a warm-blooded animal, especially a human.
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