Benjamin Stone Amidon,David P. Cardin,Alexandra E. Gould,Paul D. Greenspan,Sean J. Harrison
申请号：
US14419000
公开号：
US09593121B2
申请日:
2013.08.02
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed are chemical entities that inhibit Uba6, each of which is a compound of Formula (I) or a pharmaceutically acceptable salt thereof, wherein R*1 is —H or —CH3； and Y is Formula (II) or Formula (III), wherein R2 is —H, —CH3 or C1-4 alkyloxycarbonyl； and RS7.1, RS7.2 and RS8.1 are defined herein； pharmaceutical compositions comprising the chemical entities； and methods of using the chemical entities. These chemical entities are useful for treating disorders, particularly cell proliferation disorders, including cancers.
